Cytomegalovirus (CMV) is a common virus spread through bodily fluids and poses a risk to infants, young children, and the immunocompromised. While most infants remain asymptomatic, symptomatic individuals may experience fever, irritability, and organ involvement. Diagnosis involves blood tests or alternative methods, and treatment includes antiviral medications. Prevention focuses on hand hygiene and vaccination during pregnancy. Healthcare professionals involved in CMV management include pediatricians and infectious disease specialists. Ongoing research aims to improve vaccine development, understand long-term effects, and promote education and support for affected individuals.